Cleveland, Ohio clinic performs US’s first face transplant

Thursday, December 18, 2008

A team of eight transplant surgeons in Cleveland Clinic in Ohio, USA, led by reconstructive surgeon Dr. Maria Siemionow, age 58, have successfully performed the first almost total face transplant in the US, and the fourth globally, on a woman so horribly disfigured due to trauma, that cost her an eye. Two weeks ago Dr. Siemionow, in a 23-hour marathon surgery, replaced 80 percent of her face, by transplanting or grafting bone, nerve, blood vessels, muscles and skin harvested from a female donor’s cadaver.

The Clinic surgeons, in Wednesday’s news conference, described the details of the transplant but upon request, the team did not publish her name, age and cause of injury nor the donor’s identity. The patient’s family desired the reason for her transplant to remain confidential. The Los Angeles Times reported that the patient “had no upper jaw, nose, cheeks or lower eyelids and was unable to eat, talk, smile, smell or breathe on her own.” The clinic’s dermatology and plastic surgery chair, Francis Papay, described the nine hours phase of the procedure: “We transferred the skin, all the facial muscles in the upper face and mid-face, the upper lip, all of the nose, most of the sinuses around the nose, the upper jaw including the teeth, the facial nerve.” Thereafter, another team spent three hours sewing the woman’s blood vessels to that of the donor’s face to restore blood circulation, making the graft a success.

The New York Times reported that “three partial face transplants have been performed since 2005, two in France and one in China, all using facial tissue from a dead donor with permission from their families.” “Only the forehead, upper eyelids, lower lip, lower teeth and jaw are hers, the rest of her face comes from a cadaver; she could not eat on her own or breathe without a hole in her windpipe. About 77 square inches of tissue were transplanted from the donor,” it further described the details of the medical marvel. The patient, however, must take lifetime immunosuppressive drugs, also called antirejection drugs, which do not guarantee success. The transplant team said that in case of failure, it would replace the part with a skin graft taken from her own body.

Dr. Bohdan Pomahac, a Brigham and Women’s Hospital surgeon praised the recent medical development. “There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Leading bioethicist Arthur Caplan of the University of Pennsylvania withheld judgment on the Cleveland transplant amid grave concerns on the post-operation results. “The biggest ethical problem is dealing with failure — if your face rejects. It would be a living hell. If your face is falling off and you can’t eat and you can’t breathe and you’re suffering in a terrible manner that can’t be reversed, you need to put on the table assistance in dying. There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Dr Alex Clarke, of the Royal Free Hospital had praised the Clinic for its contribution to medicine. “It is a real step forward for people who have severe disfigurement and this operation has been done by a team who have really prepared and worked towards this for a number of years. These transplants have proven that the technical difficulties can be overcome and psychologically the patients are doing well. They have all have reacted positively and have begun to do things they were not able to before. All the things people thought were barriers to this kind of operations have been overcome,” she said.

The first partial face transplant surgery on a living human was performed on Isabelle Dinoire on November 27 2005, when she was 38, by Professor Bernard Devauchelle, assisted by Professor Jean-Michel Dubernard in Amiens, France. Her Labrador dog mauled her in May 2005. A triangle of face tissue including the nose and mouth was taken from a brain-dead female donor and grafted onto the patient. Scientists elsewhere have performed scalp and ear transplants. However, the claim is the first for a mouth and nose transplant. Experts say the mouth and nose are the most difficult parts of the face to transplant.

In 2004, the same Cleveland Clinic, became the first institution to approve this surgery and test it on cadavers. In October 2006, surgeon Peter Butler at London‘s Royal Free Hospital in the UK was given permission by the NHS ethics board to carry out a full face transplant. His team will select four adult patients (children cannot be selected due to concerns over consent), with operations being carried out at six month intervals. In March 2008, the treatment of 30-year-old neurofibromatosis victim Pascal Coler of France ended after having received what his doctors call the worlds first successful full face transplant.

Ethical concerns, psychological impact, problems relating to immunosuppression and consequences of technical failure have prevented teams from performing face transplant operations in the past, even though it has been technically possible to carry out such procedures for years.

Mr Iain Hutchison, of Barts and the London Hospital, warned of several problems with face transplants, such as blood vessels in the donated tissue clotting and immunosuppressants failing or increasing the patient’s risk of cancer. He also pointed out ethical issues with the fact that the procedure requires a “beating heart donor”. The transplant is carried out while the donor is brain dead, but still alive by use of a ventilator.

According to Stephen Wigmore, chair of British Transplantation Society’s ethics committee, it is unknown to what extent facial expressions will function in the long term. He said that it is not certain whether a patient could be left worse off in the case of a face transplant failing.

Mr Michael Earley, a member of the Royal College of Surgeon‘s facial transplantation working party, commented that if successful, the transplant would be “a major breakthrough in facial reconstruction” and “a major step forward for the facially disfigured.”

In Wednesday’s conference, Siemionow said “we know that there are so many patients there in their homes where they are hiding from society because they are afraid to walk to the grocery stores, they are afraid to go the the street.” “Our patient was called names and was humiliated. We very much hope that for this very special group of patients there is a hope that someday they will be able to go comfortably from their houses and enjoy the things we take for granted,” she added.

In response to the medical breakthrough, a British medical group led by Royal Free Hospital’s lead surgeon Dr Peter Butler, said they will finish the world’s first full face transplant within a year. “We hope to make an announcement about a full-face operation in the next 12 months. This latest operation shows how facial transplantation can help a particular group of the most severely facially injured people. These are people who would otherwise live a terrible twilight life, shut away from public gaze,” he said.

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26 December

Google provides Gmail access to American cell phone customers

Wednesday, August 24, 2005

Gmail, Google’s popular e-mail service launched earlier last year, is now available to any American cell phone user via text messaging.

Cell phone owners can send Google their phone number, and are then sent an access code via SMS that enables them to open an account. Google has stated that the number is only used to “manage the number of accounts created per phone”, and that it “will never be sold or shared for marketing purposes” without the user’s permission.

The service is not necessarily free — cell phone service providers may charge for the delivery of the code.

While the system currently only works in the U.S., Google says it has plans to add more countries.

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22 December

Fifth bomb discovered in London after July 21 attacks

Monday, July 25, 2005

A suspect package discovered in Little Wormwood Scrubs, west London is apparently a fifth bomb made to the same design as those used in the 21 July attacks. The device was subjected to controlled explosion by the police over the weekend and its discovery has led to speculation that a fifth bombing attempt may have been intended that day. The device was apparently a nail bomb.

Little Wormwood Scrubs is just north of Shepherd’s Bush (scene of one of Thursday’s bombing attempts) and White City (the location of the BBC’s TV centre). It also borders on North Pole sidings, which are used by the Eurostar cross-channel train which travels through the Channel Tunnel.

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22 December

The Yes Men troll Wharton Business School with slavery proposal

Wednesday, November 15, 2006

The anti-globalization culture jamming group The Yes Men recently delivered a presentation at a Wharton Business School conference on trade and investment in Africa.

A performance artist, using the name Hanniford Schmidt, pretending to be a WTO representative, announced a new WTO initiative for “full private stewardry of labor” in some parts of Africa. His talk attempted to make clear that this meant slavery.

“This is what free trade’s all about,” said Schmidt. “It’s about the freedom to buy and sell anything—even people.”

Schmidt reported that “One conference attendee asked what incentive employers had to remain as stewards once their employees are too old to work or reproduce” but that “there were no other questions from the audience that took issue with Schmidt’s proposal.”

Wharton Business School placed a notice on the conference site stating that their invitation of Schmidt had been based upon his misrepresentation of himself as a representative of the WTO, and that they do not endorse his views.

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21 December

Surgeons reattach boy’s three severed limbs

Tuesday, March 29, 2005A team of Australian surgeons yesterday reattached both hands and one foot to 10-year-old Perth boy, Terry Vo, after a brick wall which collapsed during a game of basketball fell on him, severing the limbs. The wall gave way while Terry performed a slam-dunk, during a game at a friend’s birthday party.

The boy was today awake and smiling, still in some pain but in good spirits and expected to make a full recovery, according to plastic surgeon, Mr Robert Love.

“What we have is parts that are very much alive so the reattached limbs are certainly pink, well perfused and are indeed moving,” Mr Love told reporters today.

“The fact that he is moving his fingers, and of course when he wakes up he will move both fingers and toes, is not a surprise,” Mr Love had said yesterday.

“The question is more the sensory return that he will get in the hand itself and the fine movements he will have in the fingers and the toes, and that will come with time, hopefully. We will assess that over the next 18 months to two years.

“I’m sure that he’ll enjoy a game of basketball in the future.”

The weight and force of the collapse, and the sharp brick edges, resulted in the three limbs being cut through about 7cm above the wrists and ankle.

Terry’s father Tan said of his only child, the injuries were terrible, “I was scared to look at him, a horrible thing.”

The hands and foot were placed in an ice-filled Esky and rushed to hospital with the boy, where three teams of medical experts were assembled, and he was given a blood transfusion after experiencing massive blood loss. Eight hours of complex micro-surgery on Saturday night were followed by a further two hours of skin grafts yesterday.

“What he will lose because it was such a large zone of traumatised skin and muscle and so on, he will lose some of the skin so he’ll certainly require lots of further surgery regardless of whether the skin survives,” said Mr Love said today.

The boy was kept unconscious under anaesthetic between the two procedures. In an interview yesterday, Mr Love explained why:

“He could have actually been woken up the next day. Because we were intending to take him back to theatre for a second look, to look at the traumatised skin flaps, to close more of his wounds and to do split skin grafting, it was felt the best thing to do would be to keep him stable and to keep him anaesthetised.”

Professor Wayne Morrison, director of the respected Bernard O’Brien Institute of Microsurgery and head of plastic and hand surgery at Melbourne’s St Vincent’s Hospital, said he believed the operation to be a world first.

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20 December

Mayor of Flint, Michigan resigns for health reasons

Wednesday, February 11, 2009

Citing health reasons, the Mayor of Flint, Michigan, Don Williamson announced Monday at an 11:20 A.M. news conference that he was resigning from office effective Sunday February 15, 2009 at midnight. Williamson, age 75, indicated that he had multiple sinus infections and kidney stones since November 1 and his doctors wanted him to slow down by reducing his schedule.

A number of events has lead to speculation about Williamson’s resignation. His interim Police Chief, David Dicks, has been charged with defrauding the United States government stemming from the Federal investigation into his father’s security company, City Security, and its contract with Career Alliance in January. Further, a recall election was scheduled for February 24. The snap selection of Michael Brown to be the new Flint City Administrator and his current City Administrator Darryl Buchanan to the non-City Charter position of “deputy mayor” last week Wednesday. Last Thursday a press conference, originally announced to explain the switch in City Administrators and the position of “deputy mayor,” was canceled. And finally, on Friday the Interim Police Chief David Forystek was replaced with a new Interim Police Chief, John Keahey. This returned Forystek to department’s traffic bureau.

Over the last weekend, Williamson denied the rumors. Buchanan was at the press conference while Brown did not attend.

Williamson is a multi-millionaire. He is majority stockholder and chairman of the publicly traded The Colonel’s International Inc. (Nasdaq:COLO).

Williamson first stepped onto the political field by running for Mayor of Flint in 1991 but failed to get out the primary. In 1999 he lost to Woodrow Stanley in the general election. In 2003 election — the first full term election after the recall of Stanley — Williamson won the office of Mayor, while the city was still under state financial administration, succeeding Mayor James W. Rutherford into office.

In 2007, Williamson won a narrow re-election over Dayne Walling. He was only drawing a US$1 per year salary. A number of problems have cropped up since then including budget deficits, layoffs, and proposed drag strip.

Some leaders in the community that were surprised at his resignation. The Flint Journal quoted Genesee County Prosecutor David Leyton as stating “I’m shocked.” While County Sheriff Robert Pickell stated to the Journal that he was “absolutely shocked that the mayor resigned.” Pickel added, that “with Darryl Buchanan working with Mr. Brown, it will be a good team.”

City Councilor, and Williamson opponent, Scott Kincaid is quoted by ABC 12 News as stating that this “was a super-fantastic day” for the city of Flint. City Councilor Jackie Poplar said “Hallelujah!” to ABC 12.

According to the City Charter, Michael Brown as the Flint City Administrator will take over as Temporary Mayor, with no veto nor ability to remove mayorial appointees with out City Council approval. A primary will be scheduled for the May election date and the general election in August for a replacement mayor.

The recall was based on charges that Williamson mishandled city funds and misstated the status of the city’s finances. An additional recall charge according to recall supporters was he disregarded public safety by moving to eliminate 59 police officers and nine firefighters.

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17 December

Wikinews interviews 2020 Melbourne Lord Mayor Candidate Wayne Tseng

This article mentions the Wikimedia Foundation, one of its projects, or people related to it. Wikinews is a project of the Wikimedia Foundation.

Thursday, October 22, 2020

2020 Melbourne Lord Mayor candidate Wayne Tseng answered some questions about his campaign for the upcoming election from Wikinews. The Lord Mayor election in the Australian city is scheduled to take place this week.

Tseng runs a firm called eTranslate, which helps software developers to make the software available to the users. In the candidate’s questionnaire, Tseng said eTranslate had led to him working with all three tiers of the government. He previously belonged to the Australian Liberal Party, but has left since then, to run for mayorship as an independent candidate.

Tseng is of Chinese descent, having moved to Australia with his parents from Vietnam. Graduated in Brisbane, Tseng received his PhD in Melbourne and has been living in the city, he told Wikinews. Tseng also formed Chinese Precinct Chamber of Commerce, an organisation responsible for many “community bond building initiatives”, the Lord Mayor candidate told Wikinews.

Tseng discussed his plans for leading Melbourne, recovering from COVID-19, and “Democracy 2.0” to ensure concerns of minorities in the city were also heard. Tseng also focused on the importance of the multi-culture aspect and talked about making Melbourne the capital of the aboriginals. Tseng also explained why he thinks Melbourne is poised to be a world city by 2030.

Tseng’s deputy Lord Mayor candidate Gricol Yang is a Commercial Banker and works for ANZ Banking Group.

Currently, Sally Capp is the Lord Mayor of Melbourne, the Victorian capital. Capp was elected as an interim Lord Mayor in mid-2018 after the former Lord Mayor Robert Doyle resigned from his position after sexual assault allegations. Doyle served as the Lord Mayor of Melbourne for almost a decade since 2008.

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16 December

United States Homeland Security network monitors suspicious activity

Wednesday, August 3, 2005

The United States Department of Homeland Security (DHS) is deploying its new Homeland Security Information Network – Secret (HSIN-Secret) in all 50 state Emergency Operations Centers as well as 18 additional state and local law enforcement sites. “The secret network is a component of the HSIN, which is the primary conduit for DHS to share information on terrorist threats, suspicious activity and incident management with state, local, tribal and private-sector officials.” reports Government Computer News.

Development on this $350 million system by Northrop Grumman Corporation was begun in March of 2004 with basic operation achieved in just 4 months.

“The Homeland is more secure when each hometown is more secure,” said Secretary of Homeland Security Tom Ridge in DHS’s February 24, 2004 press release that launched the program. “Future program expansion will include the county level, communication at the classified SECRET level, and the involvement of the private sector.” it continues.

With the “Secret” component in place, classified information can now be disseminated to authorized individuals at all levels of government and business throughout the country almost instantly. HSIN lets most government agencies as well as many private companies doing business with the government share information on the whereabouts and suspicious activities of anyone that comes to their attention. Internal policies and the judgement of the system’s users provide privacy and civil rights protections, while who can access the system is determined by DHS.

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13 December

Australian rules football: Bairnsdale join Gippsland League, will play first game in Warragul

Thursday, December 23, 2010

Bairnsdale will return to Gippsland’s major Australian rules football league after members voted to join the Gippsland League (GL). The GL, East Gippsland Football League and the Victorian Country Football League, regional Victoria’s governing Aussie rules body, have all approved the move.

Round 1, 2011

April 9Warragul vs. BairnsdaleWonthaggi vs. MorwellTraralgon vs. Leongatha

April 10Maffra vs. SaleDrouin vs. Moe

Bairnsdale will field teams in the seniors, under 18 and under 16 grades, but not a reserves side like the rest of the competition. Players not selected in the senior side will be able to play for a club in the East Gippsland minor league, under a unique transfer agreement.

They will play their first game back in the major league in Warragul on April 9 before playing their first home game against Moe a week later.

Their furthest away game will be to Wonthaggi – a one way trip of approximately 224 kilometres.

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9 December

Cleveland, Ohio clinic performs US’s first face transplant

Thursday, December 18, 2008

A team of eight transplant surgeons in Cleveland Clinic in Ohio, USA, led by reconstructive surgeon Dr. Maria Siemionow, age 58, have successfully performed the first almost total face transplant in the US, and the fourth globally, on a woman so horribly disfigured due to trauma, that cost her an eye. Two weeks ago Dr. Siemionow, in a 23-hour marathon surgery, replaced 80 percent of her face, by transplanting or grafting bone, nerve, blood vessels, muscles and skin harvested from a female donor’s cadaver.

The Clinic surgeons, in Wednesday’s news conference, described the details of the transplant but upon request, the team did not publish her name, age and cause of injury nor the donor’s identity. The patient’s family desired the reason for her transplant to remain confidential. The Los Angeles Times reported that the patient “had no upper jaw, nose, cheeks or lower eyelids and was unable to eat, talk, smile, smell or breathe on her own.” The clinic’s dermatology and plastic surgery chair, Francis Papay, described the nine hours phase of the procedure: “We transferred the skin, all the facial muscles in the upper face and mid-face, the upper lip, all of the nose, most of the sinuses around the nose, the upper jaw including the teeth, the facial nerve.” Thereafter, another team spent three hours sewing the woman’s blood vessels to that of the donor’s face to restore blood circulation, making the graft a success.

The New York Times reported that “three partial face transplants have been performed since 2005, two in France and one in China, all using facial tissue from a dead donor with permission from their families.” “Only the forehead, upper eyelids, lower lip, lower teeth and jaw are hers, the rest of her face comes from a cadaver; she could not eat on her own or breathe without a hole in her windpipe. About 77 square inches of tissue were transplanted from the donor,” it further described the details of the medical marvel. The patient, however, must take lifetime immunosuppressive drugs, also called antirejection drugs, which do not guarantee success. The transplant team said that in case of failure, it would replace the part with a skin graft taken from her own body.

Dr. Bohdan Pomahac, a Brigham and Women’s Hospital surgeon praised the recent medical development. “There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Leading bioethicist Arthur Caplan of the University of Pennsylvania withheld judgment on the Cleveland transplant amid grave concerns on the post-operation results. “The biggest ethical problem is dealing with failure — if your face rejects. It would be a living hell. If your face is falling off and you can’t eat and you can’t breathe and you’re suffering in a terrible manner that can’t be reversed, you need to put on the table assistance in dying. There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Dr Alex Clarke, of the Royal Free Hospital had praised the Clinic for its contribution to medicine. “It is a real step forward for people who have severe disfigurement and this operation has been done by a team who have really prepared and worked towards this for a number of years. These transplants have proven that the technical difficulties can be overcome and psychologically the patients are doing well. They have all have reacted positively and have begun to do things they were not able to before. All the things people thought were barriers to this kind of operations have been overcome,” she said.

The first partial face transplant surgery on a living human was performed on Isabelle Dinoire on November 27 2005, when she was 38, by Professor Bernard Devauchelle, assisted by Professor Jean-Michel Dubernard in Amiens, France. Her Labrador dog mauled her in May 2005. A triangle of face tissue including the nose and mouth was taken from a brain-dead female donor and grafted onto the patient. Scientists elsewhere have performed scalp and ear transplants. However, the claim is the first for a mouth and nose transplant. Experts say the mouth and nose are the most difficult parts of the face to transplant.

In 2004, the same Cleveland Clinic, became the first institution to approve this surgery and test it on cadavers. In October 2006, surgeon Peter Butler at London‘s Royal Free Hospital in the UK was given permission by the NHS ethics board to carry out a full face transplant. His team will select four adult patients (children cannot be selected due to concerns over consent), with operations being carried out at six month intervals. In March 2008, the treatment of 30-year-old neurofibromatosis victim Pascal Coler of France ended after having received what his doctors call the worlds first successful full face transplant.

Ethical concerns, psychological impact, problems relating to immunosuppression and consequences of technical failure have prevented teams from performing face transplant operations in the past, even though it has been technically possible to carry out such procedures for years.

Mr Iain Hutchison, of Barts and the London Hospital, warned of several problems with face transplants, such as blood vessels in the donated tissue clotting and immunosuppressants failing or increasing the patient’s risk of cancer. He also pointed out ethical issues with the fact that the procedure requires a “beating heart donor”. The transplant is carried out while the donor is brain dead, but still alive by use of a ventilator.

According to Stephen Wigmore, chair of British Transplantation Society’s ethics committee, it is unknown to what extent facial expressions will function in the long term. He said that it is not certain whether a patient could be left worse off in the case of a face transplant failing.

Mr Michael Earley, a member of the Royal College of Surgeon‘s facial transplantation working party, commented that if successful, the transplant would be “a major breakthrough in facial reconstruction” and “a major step forward for the facially disfigured.”

In Wednesday’s conference, Siemionow said “we know that there are so many patients there in their homes where they are hiding from society because they are afraid to walk to the grocery stores, they are afraid to go the the street.” “Our patient was called names and was humiliated. We very much hope that for this very special group of patients there is a hope that someday they will be able to go comfortably from their houses and enjoy the things we take for granted,” she added.

In response to the medical breakthrough, a British medical group led by Royal Free Hospital’s lead surgeon Dr Peter Butler, said they will finish the world’s first full face transplant within a year. “We hope to make an announcement about a full-face operation in the next 12 months. This latest operation shows how facial transplantation can help a particular group of the most severely facially injured people. These are people who would otherwise live a terrible twilight life, shut away from public gaze,” he said.

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9 December